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Explore our products: The Receptor Profiles: Where Retatrutide and Tirzepatide Diverge Tirzepatide is a dual agonist at the GLP-1 receptor (GLP-1R) and the glucose-dependent insulinotropic polypeptide receptor (GIPR)

doi:10.1038/s41746-024-01112-w

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That is higher than placebo (4.9%) but actually lower than the 18.2% reported in TRIUMPH-4

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