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However, a set of challenges impede delivering peptides to the brain, including low metabolic stability and poor penetration of the blood-brain barrier

The active caspase-1 converts pro-IL-18 and pro-IL-1 into IL-18 and IL-1, which further induces an inflammatory response and triggers pyroptosis [74, 88]

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Nevi on the scalp Clinical features Nevi on the scalp occur most frequently on the occipital region, followed by left parietal region, right parietal region, and frontal region (Fig 25.69)

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