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We appreciate commenters' recommendations to reconsider the weightings of the measure groups that contribute to the Overall Hospital Quality Star Rating, implement a customized weighting scheme, or separate out the HAI measures from the Safety of Care measure group

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Low SAM, excessive methylation demand, impaired creatine synthesis, reduced glutathione availability and oxidative stress may place additional strain on mitochondria, potentially contributing to fatigue, variable cognitive stamina, sensory sensitivity, poor stress tolerance and slow recovery from illness

Frequency: Once per day (subcutaneous injection)