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Second, oxidation becomes a factor

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FTH1, which is involved in iron storage

Ferroptosis can be triggered by GSH depletion, which can be achieved by inhibiting GSH biosynthesis (e.g., buthionine sulfoximine (BSO) inhibits -glutamylcysteine synthetas (-GCS)) or blocking the uptake of cysteine from the extracellular environment (e.g., erastin inhibits the Xc system) [126, 127]

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Daily oral semaglutide and once weekly injectable semaglutide have a generally similar efficacy and safety profile