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Interestingly, GLP-1Rs are abundantly expressed not only in the pancreas and gastrointestinal tract but also in other organs, such as the lung [247]

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Dosing tiers: Oral administration (500 mcg to 1.5 mg/day) targets gut-specific inflammation: IBD, colitis, and intestinal barrier dysfunction

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like all therapies, GLP-1s can cause side effects including nausea, vomiting and other gastrointestinal issues

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