[7] The concentration of glutathione in the cytoplasm is significantly higher (ranging from 0.5-10 mM) compared to extracellular fluids (2-20 M), reaching levels up to 1000 times greater

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Stepwise approach to elevated aminotransferases Figure re-drawn from BioRender Cholestatic liver disease often presents with elevated ALP, with or without bilirubin elevation
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These factors can include the duration of treatment, insurance coverage and specific dosage of the medication