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Clinical course The clinical course of APAP hepatotoxicity in patients with a single overdose can be classically divided into 4 sequential stages (table below ), however, it should be noted that the course is variable and may not follow the four-stage sequential pattern seen after a single oral ingestion

The discussion also touches upon recent research findings and potential future uses in the field

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doi:10.1002/nbm.4227 112. Shimizu, T., Iwanaga, M., Yasunaga, A., Urata, Y., Goto, S., Shibata, S., & Kondo, T