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doi: 10.3389/fphar.2018.00891 120 ZampeliEVlachoyiannopoulosPGTzioufasAG

Furthermore, bile acids exhibit concentration-dependent regulation of respiratory tract antimicrobial peptides and innate immune responses

By keeping oxidative stress in check, it prevents the cascade of signals that lead to chronic inflammation

Ongoing challenges to trial conduct include the substances short half-life, the availability of unregulated commercial products, and ensuring protocol compliance

While injection site reactions occur in approximately 3.4% of patients in clinical trials, most cases are mild and resolve spontaneously

At clinically supervised dosing, reported adverse events are rare and typically limited to transient injection-site erythema