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Apoptosis can be initiated via three principal pathways: the extrinsic (death receptor) pathway, the intrinsic (mitochondrial) pathway, and the endoplasmic reticulum (ER) stress pathway (Figure 2A)

The brain is highly susceptible to oxidative stress, which increases during ageing and is considered a major contributor to neurodegeneration

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Numerous nonclinical and clinical studies have investigated ALA for treating diabetic peripheral neuropathy (DPN) and various other diseases

Without any genetic manipulation, bone morphogenetic protein 7 induces the conversion of adult human nonendocrine pancreatic tissue into endocrine cell types[99]

What matters is having a healthy ratio of fat to muscle