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Due to their unstable nature, free radicals cause DNA and protein damage

doi: 10.1002/ana.21800 79 HohlfeldR.DornmairK.MeinlE.WekerleH

Store at room temperature and protect from light

Patients with OA exhibit elevated iron levels in synovial tissue, and the impairment of iron homeostasis-regulating genes causes cellular iron accumulation, resulting in heightened production of ROS as well as the increased level of collagen II and MMP13, which are established hallmarks of OA [85] (Figure 2)

Long-term follow-up examining functional scales such as ICARS and survival measures will help validate riboflavins role