Search Strategy and Selection Criteria Data for this Review were identified by searches of MEDLINE, Current Contents, PubMed, and references from relevant articles using the search terms GLP-1, cardiovascular, neurological, endocrine and cancer
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Its history spans decades, with clinical use dating back to the late 1950s, and it was FDA-approved for type 2 diabetes mellitus in the mid-1990s
Promising treatments targeting the IFN- chemokine axis, JAK-STAT pathway, and Nrf2-ARE pathway, have recently emerged ( Figure 2 )
In severely affected livers, more severe chronic lesions can be observed
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