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These compounds interact with receptors on L-cells, triggering signaling pathways that stimulate the secretion of GLP-1

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Participants were randomized to receive weekly subcutaneous doses of retatrutide (1 mg, 4 mg, 8 mg, or 12 mg) or placebo for 48 weeks

In 1911 he had to flee his studies in Tbingen when it came to light that he had taken part in a duel with a fellow medical student