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Clinical trials comparing patients who lost weight through GLP-1 therapy versus those who lost equivalent weight through diet alone found that GLP-1 recipients often maintained better blood pressure control, suggesting the medication provides direct cardiovascular effects beyond caloric reduction

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L-carnitine also supports electron transport chain function and helps remove toxic acyl-CoA metabolites from mitochondria via carnitine acyltransferases

AJR Am J Roentgenol

2013, 305 (2): E161-70