Medicamentos encontrados nas chamadas canetas emagrecedoras, como a liraglutida (Saxenda e Victoza), a semaglutida (Ozempic, Wegovy e Rybelsus) e a tirzepatida (Mounjaro e Zepbound), so classificados como agonistas ou anlogos de GLP-1
Retatrutide includes GLP-1 receptor activity, but it is designed as a triple agonist that also targets GIP and glucagon receptors
Compounded drugs are not FDA-approved
Structural basis for ligand recognition of incretin receptors
By enhancing insulin secretion and reducing glucagon levels, these drugs help maintain blood sugar within target ranges and reduce the risk of diabetes-related complications
The medications in this class include semaglutide, sold as Ozempic for diabetes and Wegovy for weight loss, and tirzepatide, sold as Mounjaro for diabetes and Zepbound for weight management