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Drug Metab Dispos 35:1009-1016, 2007

The successful combination of this model with the redox cycling model was proven by recapitulation of Figs 2 and 6 from the Reed et al

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Studies have reported defective cholesterol metabolism in the brains of ALS patients and abnormal lipid droplet accumulation in astrocytes, particularly in regions like the motor cortex and spinal cord (Chaves-Filho et al., 2019)

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This highlights the importance for men who are looking to conceive to ensure that their levels are adequate before conception happens to avoid any fertility issues that a deficiency can cause