To sum up, GLP-1RAs improve cardiomyocyte/cardiac fibroblast dysfunction by making balancing energy metabolism, and multiple pathways related to AMPK to inhibit cardiac apoptosis
Unlike GLP-1, GIP also promotes GCG release in a glucose-dependent way
Hence, our data also support a previously unrecognized function of GSH in the protection against FA toxicity, and an evolutionary conserved mechanism that maintains GSH:GSSG balance by salvaging reduced GSH from FA-GSH products
[DOI] [PubMed] [Google Scholar] 72.Tosatto S.C.E., Bosello V., Fogolari F., Mauri P., Roveri A., Toppo S., Floh L., Ursini F., Maiorino M
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