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Clinical development has three main strategies: traditional approaches, enhancement, and exploratory routes

While tissue culture models are also extremely useful in understanding the biology of PCa, but they cannot recapitulate the complex cellular interactions within the tumor microenvironment that play a key role in cancer initiation and progression

Simultaneously, these drugs suppress glucagon secretion , a hormone that raises blood glucose, thereby preventing excessive glucose production by the liver

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This metabolic shift can lower total caloric intake by 30-40% during early treatment phases