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Rats: Sprague Dawley rats male 400-450 g Administration: 3-Nitropropanoic acid 750 nmol/side (in 1 L PBS) bilateral intrastriatal injection (AP = + 1.5 mm

Neuropsychopharmacology 2021;46:227228.ArticlePubMedPMC 76

Plasmodium falciparum in vitro continuous culture conditions: A comparison of parasite susceptibility and tolerance to anti-malarial drugs throughout the asexual intra-erythrocytic life cycle

Peptide dosages are often in micrograms, requiring careful attention to detail

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What it's studied for In animals and in cells, dihexa has been looked at for: Memory and learning in rodents mostly the Morris water maze, a test where a rat has to remember where a hidden platform is Models of Alzheimer's disease for example, in genetically modified mice bred to develop Alzheimer's-like brain changes Models of Parkinson's disease and motor problems Growing new synapses in hippocampal cells in a dish There's also a genuinely mundane use worth knowing about, because it's revealing: dihexa shows up in stem cell laboratories as a reagent a cheap chemical stand-in for an expensive growth factor, used to help turn stem cells into liver cells in a dish