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BMDM: bone marrow-derived macrophages
Mechanistically, an in vitro study found that exendin-4 inhibited the secretion of IL-1 and TNF- from mouse colonic smooth muscle cells (CSMCs) via the pathway mediated by cAMP and NF-B, thereby exerting anti-inflammatory effects [218]
Assessment The single primary outcome was defined as the change of triglyceride (TG) level
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Analytical Verification (COA) Each batch of AOD-9604 supplied by Grail Formula undergoes independent third-party laboratory verification to confirm compound identity, assay content, purity and microbiological safety