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Furthermore, GLP-1R activation can prevent arterial restenosis through inhibiting VSMC proliferation and migration via stress-associated endoplasmic reticulum protein 1 (SERP1) [131]

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Discontinuation Rates Treatment Discontinuation Due to Adverse Events: Retatrutide 9mg: 12.2% Retatrutide 12mg: 18.2% Placebo: 4.0% Interestingly, some discontinuations were attributed to "perceived excessive weight loss" participants felt they were losing weight too rapidly or had reached their desired weight and chose to discontinue