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By week 12, participants on the 12mg dose had already shed an average of 9.8% of body weight

The SURMOUNT trials for tirzepatide showed average losses of up to 22.5% of body weight figures that were previously only achievable with bariatric surgery

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One study found that people who stopped taking tirzepatide regained the least amount of weight if they stuck to regular lifestyle consultations, which are check-ins to get support while sticking with healthy habits