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This is a once-weekly subcutaneous injection that affects GIP (glucose-dependent insulinotrophic polypeptide) receptor and GLP-1 (glucagon-like peptide-1) receptor agonist, both appetite hormones

If you take birth control pills and are considering or currently using semaglutide, tirzepatide, or other GLP-1 compounds, understanding this interaction is essential for maintaining reliable contraceptive coverage

The within-subject variability of bioavailability (equivalent to the within-subject variability in exposure after a single dose) was estimated to be 137%, whereas at steady state, the within-subject variability in exposure was reduced to 33%

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Last Published 05.01.2026 Effective Date: 05.01.2026 This policy addresses surgery of the hip and surgical treatment for femoroacetabular impingement (FAI) syndrome