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In solchen Fllen sollte die Anwendung nur sehr zurckhaltend oder nach fachlicher Rcksprache erfolgen

Mechanism of Action IGF-1 DES exerts its anabolic and metabolic effects through high-affinity binding to and activation of the IGF-1 receptor (IGF1R), a receptor tyrosine kinase that is widely expressed across virtually all cell types in the body and serves as the primary mediator of IGF-1's growth-promoting, anti-apoptotic, and metabolic actions

Sarma BK, Manna D, Minoura M, Mugesh G

PubMed Central , Molecules , vol

10.18632/oncotarget.7598 61 HassanniaB.VandenabeeleP.BergheT

Ceruloplasmin gene variations and substantia nigra hyperechogenicity in Parkinson disease