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The model is available in PEtab format 50 at All model analyses, parameter estimation and identifiability analysis have been carried out using the dMod 51 package for R

Temperature changes during storage or transport can also cause air to separate from the solution

Furthermore, the IGF-1 adenovirus vector, transfected to H 2 O 2 -treated hepatocytes, reversed oxidative stress-induced premature senescence via enhancing cytoplasmic AKT1p53 interaction and subsequently inhibiting nuclear p53progerin interaction

These findings have prompted interest in DSIPs relevance to research on neuroprotection, oxidative stress, and recovery from neurological insult

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