GSH is involved in the detoxification of free radicals, peroxides and xenobiotics (drugs, pollutants, carcinogens, etc.), protects biological membranes from lipid peroxidation, and is an important regulator of cell homeostasis, since it participates in signaling redox, regulation of the synthesis and degradation of proteins (S-glutathionylation), signal transduction, various apoptotic processes, gene expression, cell proliferation, DNA and RNA synthesis, etc
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This shift is particularly relevant for neuroendocrine and immunemetabolic peptides, whose physiological roles inherently span multiple organ systems
Surgical repair options include (Figures): Arterial switch (Jatene) procedure in which the great arteries are switched back to the corresponding ventricle and the coronary arteries are reimplanted in the neo-aorta
Following aseptic dissection, the heart, liver, spleen, lungs, kidneys, and pancreas were gently rinsed in sterile saline, and the excess water was removed from the filter paper and weighed to calculate the organ index
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