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In addition to decreasing the fluidity of the platelet membrane and promoting platelet aggregation, coagulation factors and PAI-1 (plasminogen activator inhibitor-1) will also increase under the condition of hyperglycemia, breaking the balance of coagulation and fibrinolysis and promoting thrombosis

The Thermo Scientific Pierce bicinchoninic acid Protein Assay Kit was used to quantify proteins in the tissue homogenates analyzed

Glucagon-Like Peptide-1 and Its Class B G ProteinCoupled Receptors: A Long March to Therapeutic Successes

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* Correspondence: Monica Barne, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

The IDH3 isoform is involved in the TCA cycle where it oxidatively decarboxylates isocitrate to 2-oxoglutarate (-ketoglutarate)