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The question is not whether the mechanism makes sense but whether clinical trials will confirm the magnitude of benefit suggested by preclinical and early observational data
Tuero C, Becerril S, Ezquerro S, Neira G, Frhbeck G, Rodrguez A
Fewer side effects: While most weight loss medications come with gastrointestinal side effects like nausea and diarrhea, the dual effect of GLP-1 and GIP means these side effects may be less severe with tirzepatide than alternatives like semaglutide
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Because of the drugs pharmacology, some symptoms may linger a bit longer than with short-acting drugs
Pediatric patients did not have type 2 diabetes mellitus
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