Treatment of PDAC with DON decreases uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) levels, which affects synthesis of the hyaluronan-rich extracellular matrix (ECM)
doi: 10.1038/sj.bjp.0703953
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Scientists are investigating how the peptide interacts with cells responsible for maintaining connective tissue structure, including fibroblasts and extracellular matrix components
