Rare side effects, occurring in fewer than 1 in 1,000 people, may involve a serious allergic reaction (also known as anaphylaxis) and angioedema, which is a type of swelling beneath the skin that can affect the face, lips, tongue or throat
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They also recommend them as a possible initial treatment in those with diabetes and certain comorbidities such as obesity, chronic kidney disease and prior significant cardiovascular events
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