doi:10.2174/1570159x13666160502153022 About the Author Scott Froum, DDS Editorial Director Scott Froum, DDS, a graduate of the State University of New York, Stony Brook School of Dental Medicine, is a periodontist in private practice at 1110 2nd Avenue, Suite 305, New York City, New York
J Colloid Interface Sci 361:270277
Based on the phenomena directly observed in the OA model, the mechanisms verified in other chronic inflammatory/degenerative diseases [such as rheumatoid arthritis (RA)], and reasonable inferences based on the cross-linkages of molecular pathways, we propose a hypothetical framework, suggesting that the gut microbiota-ferroptosis axis ma contribute to the progression of OA and explore the therapeutic potential of synergistic intervention measures targeting this axis
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PGP is a stabilising motif derived from biological observation: it resists most endopeptidases and aminopeptidases thanks to rigid prolines (pyrrolidine cycle)
