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For most patients, the muscles of the eyes and eyelids are typically the first to be affected, regardless of whether patients continue to have an ocular form of the disease or progress to the generalized type

To date, at Least 22 RNAi-based therapeutics have advanced to clinical trials, with several other candidates undergoing preliminary development phases [40]

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10.1210/jcem.76.4.8473405 [DOI] [PubMed] [Google Scholar] 4.Nauck MA, Meier JJ