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In animal studies (pigs), strong systemic wound healing was induced at approximately 1.1 mg/kg body weight, roughly 300-fold below GHK-Cu's established toxic threshold in the same model

Are there side effects

Contraindications include active skin infections at treatment sites, known copper metabolism disorders, pregnancy and breastfeeding (for injectable applications), and severe allergic reactions to copper compounds

Additionally, we found that FOXO4-DRI alleviates endothelial cell senescence induced by OGD, thereby enhancing endothelial cell function

TLR4, rather than TLR2, regulates wound healing through TGF-beta and CCL5 expression

Risks such as infection, allergic reactions, or improper administration must be considered