Vitamin Es ability to protect cell membranes makes it valuable for anyone who is not eating an antioxidant-rich diet and who leads an active lifestyle, since physical exertion increases production of free radicals.
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3.2.2 Experimental studies and mechanisms of PD Pathological accumulation of metal ions or a rapid increase in monoamine oxidase B (MAO-B) activity can induce endogenous dopamine (DA) oxidation, leading to -synuclein aggregation, mitochondrial dysfunction, and other factors contributing to the heightened incidence of PD
Use of L-carnitine In clinical studies it is important to distinguish between the physiological mechanism (what happens biochemically) and outcome (what is observed in people with objective measures)
[DOI] [PubMed] [Google Scholar] 41.Rabenstein D.L., Isab A.A., Reid R.S
Evidence supports an association between the diseases, but the exact underlying mechanisms behind the connection are still under investigation
