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The regeneration of GSH after an APAP dose is also affected by the concentration of glutamate in the liver and it is known that supplementation of rats with glutamine prior to and APAP over dose acts to preserve GSH levels

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These elements maximize the risk of hypoglycemia

However, they may cause side effects like nausea, diarrhea and skin reactions in some people

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doi: 10.1136/gutjnl-2021-324784 156 VaziriNDYuanJNorrisK