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A 2018 study published in the Journal of Law and the Biosciences found that 78% of drugs associated with new patents between 2005 and 2015 were existing medications rather than novel treatments

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J Neurochem 107:241252 Wood SJ, Yucel M, Pantelis C, Berk M (2009) Neurobiology of schizophrenia spectrum disorders: the role of oxidative stress