The dose conversion data suggests that maximum semaglutide roughly corresponds to tirzepatide 10-15mg, so maximum tirzepatide provides meaningfully more metabolic stimulus than maximum semaglutide
It's the needle
[DOI] [PMC free article] [PubMed] [Google Scholar] 199.Haney M.J., Klyachko N.L., Zhao Y., Gupta R., Plotnikova E.G., He Z., Patel T., Piroyan A., Sokolsky M., Kabanov A.V., et al
Wijarnpreecha, K., Boonpheng, B., Thongprayoon, C., Jaruvongvanich, V
The Intensifying GLP-1 Race While Novo Nordisk recently secured FDA approval for an oral version of semaglutide becoming the first to market an oral GLP-1RA for obesity Eli Lilly continues to lead in injectable sales with: Zepbound (obesity) Mounjaro (type 2 diabetes) Lilly is also awaiting an FDA decision on its oral candidate, orforglipron