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Cross-linking changes compound these problems
doi: 10.1016/j.parkreldis.2014.01.011 121 MuellerC.PinterB.ReiterE.SchockeM.ScherflerC.PoeweW.et al
For instance, the detailed functions and precise mechanisms of biomolecules involved in oxidative stress need further elucidation
This is known as metabolic adaptation
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Steatosis and hepatitis C virus: mechanisms and significance for hepatic and extrahepatic disease
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