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At the intestinal level, TMAO can downregulate tight junction proteins, such as Claudin-1, alter the Firmicutes/Bacteroidetes ( F/B ) ratio, reduce the microbiotas resilience to stress, and promote the elevation of harmful metabolites, thereby inducing systemic inflammation (Chen et al., 2022)

NF-B activated microglia, innate immune cells in the central nervous system, can accelerate the tau seeding and propagation of tau pathology, and inactivation of this transcription factor can lead to a slow down of this propagation demonstrated in the mice model (Wang et al., 2022)

[PubMed] [Google Scholar] 107.Gee B.E

While the skepticism surrounding traditional capsules is based on real digestive hurdles, liposomal technology has fundamentally changed the landscape

We DO know that food can create inflammation in the body

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