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Published findings describe effects on genes associated with antioxidant response (Nrf2 pathway), DNA repair mechanisms, ubiquitin-proteasome pathway components, and inflammatory signaling cascades

this change in the protein sequence reduces enzyme activity and therefore could influence tissue susceptibility to oxidative stress [23]

The Variable Importance in Projection (VIP) was ranked in the OPLS-DA (orthogonal projections to latent structures discriminant analysis) based on each variables total effect on the OPLS-DA model, with variables having a VIP 1 and p 2.0.CO;2 25 KimS

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B., McAlpine, J

In Crohns disease, malnutrition is present in up to 85% of patients, with active small intestinal involvement causing significant absorptive mucosal damage and blind loops resulting in bacterial overgrowth