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Figure 1 4.1 Activation of Toll-like receptors by dysbiotic microbiome affects esophageal barrier structure, epithelial repair, and triggers inflammatory responses involved in GERD G- bacteria are key producers of lipopolysaccharide (LPS), which abnormally activates a variety of Toll-like receptors (TLRs) leading to epithelial barrier dysfunction and inflammatory responses leading to GERD
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Without baseline and on-treatment measurements, the benefit of adding glutathione remains speculative
However, it should only be usedunder medical supervision as it may cause side effects, such as skin irritation or rebound hyperpigmentation if used excessively or incorrectly
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