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doi:10.2174/157015909787602788 Kappos L, Gold R, Miller DH, Macmanus DG, Havrdova E, Limmroth V, Polman CH, Schmierer K, Yousry TA, Yang M, Eraksoy M, Meluzinova E, Rektor I, Dawson KT, Sandrock AW, ONeil GN, BG-12 Phase IIb Study Investigators (2008) Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study

Mechanisms may involve enhancement of follicle stem cell activity, improvement of follicle vascularization, and anti-inflammatory effects on the follicle microenvironment

2023 Mar;38(3):805-817

Eliminates toxins, including ROS and peroxides

Effects of iron deprivation on the pathology and stress protein expression in murine X-linked muscular dystrophy

By altering muscle protein degradation rates, it could accelerate the age-related loss of muscle proteins