( Discussion A meta-analysis of four RCTs evaluating the efficacy and safety of adding basal insulin in T2DM subjects insufficiently managed using GLP-1RA showed that the free up-titration of basal insulin and GLP-1RA and switching to FRC effectively enhanced glycemic control compared to unchanged GLP-1RA but accompanied elevated hypoglycemic risk
37 YamamotoS.WatanabeB.HiratakeJ.TanakaR.OhkitaM.MatsumuraY
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The receptors of several growth factors, cytokines, and hormones are RTKs which bind to and phosphorylate different signaling transducers, e.g., members of the JAK family [37]
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9 , e016906 (2020)
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