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L-carnitine is available both through dietary sources such as red meat, fish, and dairy, and through supplements, widely used to enhance athletic performance, promote weight loss, and boost cognitive function

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Ahanger, Prawez AA, Kumar S, Prasad D, Amarpal R, Tandan SK, et al

Daily dosing is both a pro and a con

Data were low-pass filtered at 2 kHz and a 5-ms template (2 ms baseline, 2 pA amplitude, 0.5 ms rise time, and 1 ms decay time) was used to detect spontaneous EPSCs

However, Hebbian-type plasticity rules introduce an intrinsic positive feedback on synaptic weight changes, making synapses prone to runaway potentiation or depression and eventual saturation, and making neuronal activity prone to runaway activation or complete silencing