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In a New York Times opinion column explaining why the FDA is taking action this week, Commissioner Marty Makary highlighted online pharmacies marketing drugs without presenting an adequate balance of risks, and in particular a Super Bowl ad from Hims & Hers parading the benefits of GLP-1 drugs without any mention of side effects. But the compounding letters scope is narrower than that messaging suggests

Finally, all the treatment groups, except melatoninbetaine, GAbetaine, and melatoninGA, significantly increased renalase levels

PMID 41723539

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