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delivery is however to prove that sufficient amounts of therapeutics reach circulation, and efficacy at the site of action

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Nature 496 , 513517 (2013)

Hvidt and Linderstrom-Lang, 1955

CHARMM36 all-atom additive protein force field: validation based on comparison to NMR data

Instead, it is commonly used as a systems-level neuromodulatory probe to study interactions between sleep architecture, stress signaling, and neuroendocrine regulation