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Somewhat contradictory to the observations in animals, Savage et al (56) reported 27 prepubertal children with severe GH insensitivity syndrome (GHIS or Severe Primary IGF Deficiency (SPIGFD)) to have a median (range) birth weight SDS of -0.72 (1.75 - (-3.29)) and birth length SDS of -1.59 (0.63 - (-3.63))

The significance of finding your Ikigai lies in its holistic impact on various aspects of ones life: Enhancing happiness and well-being Studies reveal that having Ikigai is linked to reduced anxiety and depression, heightened positive emotions, and increased life satisfaction

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Cell, 2017