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Such mechanisms could detrimentally impair astrocyte functions either through the loss or down-regulation of essential homoeostatic functions or through the gain of detrimental effects, or combinations of both

By doing so, we aspire to not only enrich the understanding of the diseases origins but also pinpoint promising therapeutic avenues

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2.5 Ferroptosis and other regulatory mechanisms 2.5.1 p53-mediated ferroptosis Research has shown that p53 has a complex dual mechanism for regulating cellular ferroptosis through transcription and translation (82)

Clinical and epidemiological features