Dapagliflozin monotherapy in drug-nave patients with diabetes: A randomized-controlled trial of low-dose range
Going straight to maintenance doses means tissue concentrations never reach therapeutic threshold
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The VTA is the origin of the mesolimbic dopamine pathway the same circuit that underlies reward, craving, and anhedonia
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[DOI] [PMC free article] [PubMed] [Google Scholar] 78.Loomba R., Abdelmalek M.F., Armstrong M.J., Jara M., Kjr M.S., Krarup N., Lawitz E., Ratziu V., Sanyal A.J., Schattenberg J.M., et al