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Contraindication: Do not use in subjects with uncontrolled high blood pressure.

Ulcers are often characterized by more severe abdominal pain, indigestion and heartburn

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Energy levels remain stable

8.4 Pediatric Use The safety and effectiveness of TRULICITY as an adjunct to diet and exercise to improve glycemic control in pediatric patients 10 years of age and older with type 2 diabetes mellitus have been established

The ring closure (marked by a dashed arrow) between the last isoleucine and threonine is catalysed by the thioesterase domains during molecule off-loading, resulting in teixobactin