semaglutide aspiration case report anesthesia 2023 Perioperative management of patients taking glucagon-like peptide 1 receptor agonists: Society for Perioperative Assessment and Quality Improvement (SPAQI) multidisciplinary consensus statement GLP-1 drugs and aspiration risk

Clinical trials are raising the bar Retatrutide ~24% weight loss (triple agonist) MariTide 1216% weight loss (GLP-1 + GIP antagonist) CagriSema up to 20% weight loss + ~2% HbA1c drop Orforglipron oral GLP-1, HbA1c 1.5%, weight 7.6% IcoSema weekly sema + once-weekly insulin Even more exciting

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Seizures have been reported in dogs receiving this class of drugs, even in dogs without a history of seizures

In clinical trials, tirzepatide produced somewhat greater average weight loss, likely because it works on two hormone pathways (GLP-1 and GIP) instead of one

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Many people who feel chest pain worry that it is from a heart attack